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Hengming Ke | Researchclopedia

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Hengming Ke

University of North Carolina at Chapel Hill

164

Works

9,845

Citations

53

h-index

95

i10-index

Research Topics

Phosphodiesterase function and regulation Cholinesterase and Neurodegenerative Diseases Chemical synthesis and alkaloids

Affiliations

University of North Carolina at Chapel Hill1991–2025

Harvard University1987–1991

Johns Hopkins University2002–2002

Sun Yat-sen University2008–2015

University of California, Los Angeles2002–2003

Top Works

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

Sung Jun Park,Faiyaz Ahmad,et al.

20121,323 citations

Synthesis and Catalytic Reactions

Enzyme Structure and Function

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

Junli Liu,Hongguang Xia,et al.

2011805 citations

Advances in targeting cyclic nucleotide phosphodiesterases

Donald H. Maurice,Hengming Ke,et al.

2014757 citations

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

Rachael P. Norris,William J. Ratzan,et al.

2009509 citations

Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity

Robert X. Xu,Anne M. Hassell,et al.

2000333 citations

Familial Parkinson's Disease-associated L166P Mutation Disrupts DJ-1 Protein Folding and Function

James A. Olzmann,Keith Brown,et al.

2004273 citations

Crystal structure of calcineurin–cyclophilin–cyclosporin shows common but distinct recognition of immunophilin–drug complexes

Qing Huai,Hwa-Young Kim,et al.

2002271 citations

The Monofunctional Chorismate Mutase from Bacillus subtilis

Yuh Min Chook,Joseph V. Gray,et al.

1994180 citations

Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12–FK506 in <i>Cryptococcus neoformans</i>

Deborah S. Fox,Maria Cristina Cruz,et al.

2001180 citations