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Nathalie Méthot | Researchclopedia

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Nathalie Méthot

40

Works

3,717

Citations

30

h-index

33

i10-index

Research Topics

RNA Research and Splicing RNA and protein synthesis mechanisms Nicotinic Acetylcholine Receptors Study

Affiliations

University of Bern1995–1995

Texas Tech University1998–1998

Merck & Co., Inc., Rahway, NJ, USA (United States)2004–2013

University of Ottawa1994–2001

University of Zurich1999–2001

Top Works

Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Arnim Pause,Nathalie Méthot,et al.

1994392 citations

RNA regulation and disease

Protease and Inhibitor Mechanisms

Hedgehog Controls Limb Development by Regulating the Activities of Distinct Transcriptional Activator and Repressor Forms of Cubitus interruptus

Nathalie Méthot,Konrad Basler

1999377 citations

The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.

Arnim Pause,Nathalie Méthot,et al.

1993280 citations

Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR

N. B. Abraham,David F. Stojdl,et al.

1999230 citations

Suppressor of Fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus

Nathalie Méthot,Konrad Basler

2000200 citations

A Region Rich in Aspartic Acid, Arginine, Tyrosine, and Glycine (DRYG) Mediates Eukaryotic Initiation Factor 4B (eIF4B) Self-Association and Interaction with eIF3

Nathalie Méthot,Min Soo Song,et al.

1996182 citations

An absolute requirement for Cubitus interruptus in Hedgehog signaling

Nathalie Méthot,Konrad Basler

2001153 citations

MF63 [2-(6-Chloro-1 H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation

Daigen Xu,Steven E. Rowland,et al.

2008152 citations

Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886

Denis Riendeau,Renée Aspiotis,et al.

2005142 citations