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Irma B. Stowe | Researchclopedia

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Irma B. Stowe

Beth Israel Deaconess Medical Center

22

Works

6,968

Citations

14

h-index

15

i10-index

Research Topics

Inflammasome and immune disorders Gout, Hyperuricemia, Uric Acid Cell death mechanisms and regulation

Affiliations

Beth Israel Deaconess Medical Center2025–2025

City College of San Francisco2012–2012

Department of Physiological Sciences2019–2019

UCSF Helen Diller Family Comprehensive Cancer Center2012–2012

Top Works

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki,Irma B. Stowe,et al.

20153,569 citations

Immune Response and Inflammation

Heme Oxygenase-1 and Carbon Monoxide

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

Nobuhiko Kayagaki,Michael T. Wong,et al.

20131,505 citations

NINJ1 mediates plasma membrane rupture during lytic cell death

Nobuhiko Kayagaki,Opher S. Kornfeld,et al.

2021759 citations

IRF2 transcriptionally induces <i>GSDMD</i> expression for pyroptosis

Nobuhiko Kayagaki,Bettina L. Lee,et al.

2019177 citations

A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1

Irma B. Stowe,Ellen L. Mercado,et al.

2012167 citations

Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation

Bettina L. Lee,Irma B. Stowe,et al.

2018160 citations

Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury

Nobuhiko Kayagaki,Irma B. Stowe,et al.

2023156 citations

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Lieselotte Vande Walle,Irma B. Stowe,et al.

2019151 citations

ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages

Bettina L. Lee,Kathleen M. Mirrashidi,et al.

2018138 citations