Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

Andrei V. Krivtsov | Researchclopedia

Back to researchers

Andrei V. Krivtsov

Boston Children's Hospital ORCID

143

Works

11,374

Citations

40

h-index

52

i10-index

Research Topics

Acute Myeloid Leukemia Research Protein Degradation and Inhibitors Epigenetics and DNA Methylation

Affiliations

Medical University of Lublin2010–2010

Brigham and Women's Hospital2010–2010

Boston Children's Hospital2005–2025

Memorial Sloan Kettering Cancer Center2012–2018

New York Blood Center2007–2007

Top Works

Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

Andrei V. Krivtsov,David Twomey,et al.

20061,517 citations

Cancer-related gene regulation

Histone Deacetylase Inhibitors Research

MLL translocations, histone modifications and leukaemia stem-cell development

Andrei V. Krivtsov,Scott A. Armstrong

20071,251 citations

MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

Kathrin M. Bernt,Nan Zhu,et al.

2011888 citations

The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

Jenny Wang,Andrei V. Krivtsov,et al.

2010749 citations

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

Andrei V. Krivtsov,Zhaohui Feng,et al.

2008548 citations

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

Eytan M. Stein,Guillermo Garcia‐Manero,et al.

2018450 citations

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

Andrei V. Krivtsov,Kathryn Evans,et al.

2019439 citations

A dominant-negative effect drives selection of <i>TP53</i> missense mutations in myeloid malignancies

Steffen Boettcher,Peter G. Miller,et al.

2019419 citations

Mediator kinase inhibition further activates super-enhancer-associated genes in AML

Henry E. Pelish,Brian B. Liau,et al.

2015401 citations