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D J Lew | Researchclopedia

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D J Lew

University of California, San Diego

7

Works

1,368

Citations

7

h-index

7

i10-index

Research Topics

interferon and immune responses Cytokine Signaling Pathways and Interactions Viral Infections and Immunology Research

Affiliations

University of California, San Diego1993–1993

New York University1990–1990

Rockefeller University1989–1991

Top Works

Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor.

Thomas Decker,D J Lew,et al.

1991382 citations

RNA and protein synthesis mechanisms

Immunotherapy and Immune Responses

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

D J Lew,Thomas Decker,et al.

1991272 citations

Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.

David T. Levy,D J Lew,et al.

1990218 citations

Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein.

Thomas Decker,D J Lew,et al.

1989163 citations

Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

Thomas Decker,D J Lew,et al.

1991131 citations

GHF-1-promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice.

D J Lew,Helen Brady,et al.

1993127 citations

Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways.

D J Lew,Thomas Decker,et al.

198975 citations