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Nathaniel J. Henning | Researchclopedia

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Nathaniel J. Henning

Berkeley College ORCID

17

Works

1,701

Citations

12

h-index

12

i10-index

Research Topics

Protein Degradation and Inhibitors Click Chemistry and Applications Ubiquitin and proteasome pathways

Affiliations

Novartis (Switzerland)2021–2021

Berkeley College2023–2023

Harvard University2020–2022

Middlebury College2017–2020

Innovative Genomics Institute2021–2022

Top Works

Advances in covalent drug discovery

Lydia Boike,Nathaniel J. Henning,et al.

2022728 citations

Peptidase Inhibition and Analysis

Alzheimer's disease research and treatments

Deubiquitinase-targeting chimeras for targeted protein stabilization

Nathaniel J. Henning,Lydia Boike,et al.

2022300 citations

Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

Nathaniel J. Henning,Andrew G. Manford,et al.

2022200 citations

Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC

Lydia Boike,Alexander G. Cioffi,et al.

2020154 citations

Exploring the target scope of KEAP1 E3 ligase-based PROTACs

Guangyan Du,Jie Jiang,et al.

202284 citations

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2

Guangyan Du,Jie Jiang,et al.

202155 citations

Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine

Guangyan Du,Suman Rao,et al.

202036 citations

Deubiquitinase-Targeting Chimeras for Targeted Protein Stabilization

Nathaniel J. Henning,Lydia Boike,et al.

202132 citations

Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu2+ play a major role in the oxidative stress mechanism of Alzheimer’s disease

Sebastian M. Fica-Contreras,Sydney O. Shuster,et al.

201727 citations