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Anthony Letai | Researchclopedia

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Anthony Letai

Harvard University ORCID

625

Works

40,898

Citations

84

h-index

184

i10-index

Research Topics

Acute Myeloid Leukemia Research Cell death mechanisms and regulation Chronic Lymphocytic Leukemia Research

Affiliations

Broad Institute2012–2021

Boston University2017–2017

Brigham and Women's Hospital2012–2023

Novartis (Switzerland)2015–2015

Memorial Sloan Kettering Cancer Center2012–2012

Top Works

The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim,Craig H. Mermel,et al.

20104,085 citations

RNA Interference and Gene Delivery

Acute Lymphoblastic Leukemia research

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf,Steven W. Elmore,et al.

20053,369 citations

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

Courtney D. DiNardo,Brian A. Jonas,et al.

20202,668 citations

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

Rumani Singh,Anthony Letai,et al.

20192,021 citations

Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

Courtney D. DiNardo,Keith W. Pratz,et al.

20181,826 citations

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Anthony Letai,Michael C. Bassik,et al.

20021,635 citations

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

Michael Certo,Victoria Del Gaizo Moore,et al.

20061,253 citations

Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia

Marina Konopleva,Daniel A. Pollyea,et al.

20161,040 citations

Control of mitochondrial apoptosis by the Bcl-2 family

Joslyn K. Brunelle,Anthony Letai

2009916 citations