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William J. Muller | Researchclopedia

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William J. Muller

McGill University Health Centre ORCID

581

Works

27,427

Citations

90

h-index

250

i10-index

Research Topics

HER2/EGFR in Cancer Research Monoclonal and Polyclonal Antibodies Research PI3K/AKT/mTOR signaling in cancer

Affiliations

University College Dublin2010–2010

Ontario Institute for Cancer Research2004–2004

Roche (Switzerland)2013–2013

University of Iowa2012–2012

Mount Sinai Hospital2003–2010

Top Works

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

William J. Muller,Eric Sinn,et al.

19881,169 citations

Cancer Cells and Metastasis

Immunotherapy and Immune Responses

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

Elaine Y. Lin,Joan G. Jones,et al.

20031,137 citations

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Krushna C. Patra,Qi Wang,et al.

2013845 citations

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

Eric Sinn,William J. Muller,et al.

1987799 citations

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang,Cong S. Zong,et al.

2008696 citations

Suppression of tumor growth and metastasis in Mgat5-deficient mice

Maria Granovsky,Jimmie E. Fata,et al.

2000561 citations

Oncogenes and Tumor Suppressor Genes

Eva Y‐HP Lee,William J. Muller

2010501 citations

β4 Integrin Amplifies ErbB2 Signaling to Promote Mammary Tumorigenesis

Wenjun Guo,Yuliya Pylayeva,et al.

2006454 citations

Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

Peter M. Siegel,Weiping Shu,et al.

2003427 citations