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Stephen B. Willingham | Researchclopedia

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Stephen B. Willingham

69

Works

9,401

Citations

29

h-index

34

i10-index

Research Topics

Adenosine and Purinergic Signaling Inflammasome and immune disorders Phagocytosis and Immune Regulation

Affiliations

University of North Carolina at Chapel Hill2007–2020

California Institute for Regenerative Medicine2012–2021

University of Washington2003–2003

Cancer Institute (WIA)2013–2013

University Medical Center2012–2012

Top Works

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Stephen B. Willingham,Jens-Peter Volkmer,et al.

20121,628 citations

Cancer Immunotherapy and Biomarkers

Immunotherapy and Immune Responses

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

Mark P. Chao,Siddhartha Jaiswal,et al.

2010753 citations

Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP3

Hanfen Li,Stephen B. Willingham,et al.

2008647 citations

Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

Diane Tseng,Jens-Peter Volkmer,et al.

2013638 citations

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

Joseph A. Duncan,Dan T. Bergstralh,et al.

2007483 citations

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

Jie Liu,Lijuan Wang,et al.

2015465 citations

Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein

Stephen B. Willingham,Tiago F. Outeiro,et al.

2003425 citations

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Sharareh Gholamin,Siddhartha S. Mitra,et al.

2017418 citations

NLRs at the intersection of cell death and immunity

Jenny P.‐Y. Ting,Stephen B. Willingham,et al.

2008372 citations