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James K. Hennan | Researchclopedia

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James K. Hennan

Madrigal Pharmaceuticals (United States)

73

Works

1,848

Citations

24

h-index

40

i10-index

Research Topics

Cardiac electrophysiology and arrhythmias Connexins and lens biology Ion channel regulation and function

Affiliations

Project Management Institute2009–2009

University of British Columbia1998–2001

University of California, San Francisco2005–2005

University of Toronto2009–2009

Princeton University2004–2004

Top Works

Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1: Design, Synthesis, and Preclinical Characterization

Hassan Elokdah,Magid Abou‐Gharbia,et al.

2004167 citations

Atrial Fibrillation Management and Outcomes

Blood Coagulation and Thrombosis Mechanisms

Effects of Selective Cyclooxygenase-2 Inhibition on Vascular Responses and Thrombosis in Canine Coronary Arteries

James K. Hennan,Jinbao Huang,et al.

2001162 citations

Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123)

Lene Nygaard Axelsen,Martin Stahlhut,et al.

2006133 citations

Model-Dependent Effects of the Gap Junction Conduction–Enhancing Antiarrhythmic Peptide Rotigaptide (ZP123) on Experimental Atrial Fibrillation in Dogs

Akiko Shiroshita-Takeshita,Masao Sakabe,et al.

2007132 citations

C-Reactive-Protein-Associated Increase in Myocardial Infarct Size After Ischemia/Reperfusion

Terrance D. Barrett,James K. Hennan,et al.

200292 citations

Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs

James K. Hennan,Robert E. Swillo,et al.

200685 citations

The Antiarrhythmic Peptide Analog ZP123 Prevents Atrial Conduction Slowing During Metabolic Stress

Ketil Haugan,Kristine Boisen Olsen,et al.

200571 citations

Effect of tiplaxtinin (PAI‐039), an orally bioavailable PAI‐1 antagonist, in a rat model of thrombosis

James K. Hennan,Gwen A. Morgan,et al.

200862 citations

Pharmacological Modulation of Gap Junction Function with the Novel Compound Rotigaptide: A Promising New Principle for Prevention of Arrhythmias

Anne Louise Kjølbye,Ketil Haugan,et al.

200757 citations