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Jan M. van Deursen | Researchclopedia

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Jan M. van Deursen

Mayo Clinic ORCID

160

Works

34,632

Citations

70

h-index

111

i10-index

Research Topics

Microtubule and mitosis dynamics Telomeres, Telomerase, and Senescence Genomics and Chromatin Dynamics

Affiliations

St. Jude Children's Research Hospital1996–1998

Mayo Clinic2001–2025

University Medical Center Groningen2013–2019

Harvard University1998–1998

University of Groningen2016–2019

Top Works

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Darren J. Baker,Tobias Wijshake,et al.

20113,567 citations

Cancer-related Molecular Pathways

Ubiquitin and proteasome pathways

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Darren J. Baker,Bennett G. Childs,et al.

20162,693 citations

The role of senescent cells in ageing

Jan M. van Deursen

20142,551 citations

Cellular senescence in aging and age-related disease: from mechanisms to therapy

Bennett G. Childs,Matej Durik,et al.

20152,242 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

Tsukasa Okuda,Jan M. van Deursen,et al.

19961,856 citations

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Ok Hee Jeon,Chaekyu Kim,et al.

20171,458 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

Stephan Teglund,Catriona McKay,et al.

19981,283 citations

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

Tyler J. Bussian,Asef Aziz,et al.

20181,223 citations

Senescent cells: an emerging target for diseases of ageing

Bennett G. Childs,Martina Gluscevic,et al.

20171,186 citations