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Laurent Sanière | Researchclopedia

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Laurent Sanière

Galapagos (France)ORCID

36

Works

879

Citations

12

h-index

16

i10-index

Research Topics

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Axon Guidance and Neuronal Signaling Synthesis and Catalytic Reactions

Affiliations

Centre National de la Recherche Scientifique2000–2004

Institut de Chimie des Substances Naturelles2001–2004

American Pharmacists Association2000–2001

Pliva (Croatia)2016–2016

Galapagos (France)2014–2026

Top Works

Copper-Catalyzed Nitrogen Transfer Mediated by Iodosylbenzene PhIO

Philippe Dauban,Laurent Sanière,et al.

2001287 citations

Catalytic C–H Functionalization Methods

Neonatal Respiratory Health Research

Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic

Mathieu Pizzonero,Sonia Dupont,et al.

2014109 citations

The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

Tobias Puengel,Steve De Vos,et al.

202078 citations

Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis

Niklas J. Lang,Janine Gote-Schniering,et al.

202370 citations

RETRACTED: The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models

Giovanni Luca Gravina,A. Mancini,et al.

201950 citations

Discovery of 9-Cyclopropylethynyl-2-((<i>S</i>)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-<i>a</i>]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial

Frédéric Labéguère,Sonia Dupont,et al.

202043 citations

Iminoiodane mediated aziridination of α-allylglycine: access to a novel rigid arginine derivative and to the natural amino acid enduracididine

Laurent Sanière,Loı̈c Leman,et al.

200441 citations

Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells

Francesca Megiorni,Giovanni Luca Gravina,et al.

201735 citations

Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis

Oscar Mammoliti,Adeline Palisse,et al.

202130 citations