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Martin Scheffner | Researchclopedia

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Martin Scheffner

University of Konstanz ORCID

187

Works

22,717

Citations

61

h-index

121

i10-index

Research Topics

Ubiquitin and proteasome pathways Cancer-related Molecular Pathways Glycosylation and Glycoproteins Research

Affiliations

National Institutes of Health1991–1992

Harvard University1994–1995

Technion – Israel Institute of Technology2001–2003

University of Dundee2010–2010

German Cancer Research Center1994–2007

Top Works

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Martin Scheffner,Bruce A. Werness,et al.

19903,981 citations

Peptidase Inhibition and Analysis

Cervical Cancer and HPV Research

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Martin Scheffner,Jon M. Huibregtse,et al.

19932,383 citations

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

J M Huibregtse,Martin Scheffner,et al.

19951,006 citations

Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascade

Martin Scheffner,Ulrike A. Nuber,et al.

19951,006 citations

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.

Jon M. Huibregtse,Martin Scheffner,et al.

1991881 citations

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.

Martin Scheffner,Karl Münger,et al.

1991868 citations

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

Yasuyuki Fujita,Gerd Krause,et al.

2002825 citations

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

J M Huibregtse,Martin Scheffner,et al.

1993537 citations

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

Monica Gostissa,Arnd Hengstermann,et al.

1999509 citations