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Stefan Hepbildikler | Researchclopedia

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Stefan Hepbildikler

Roche Pharma AG (Germany)

15

Works

470

Citations

10

h-index

10

i10-index

Research Topics

Protein purification and stability Viral Infectious Diseases and Gene Expression in Insects Monoclonal and Polyclonal Antibodies Research

Affiliations

Roche (Switzerland)2015–2019

John Wiley & Sons (Germany)2012–2012

Roche Pharma AG (Germany)2009–2020

CS Diagnostics2009–2019

Top Works

Determination of parameters for the steric mass action model—A comparison between two approaches

Anna Osberghaus,Stefan Hepbildikler,et al.

201293 citations

Analytical Chemistry and Chromatography

Microfluidic and Bio-sensing Technologies

Ultrafiltration concentration of monoclonal antibody solutions: Development of an optimized method minimizing aggregation

Eva Rosenberg,Stefan Hepbildikler,et al.

200975 citations

Optimizing a chromatographic three component separation: A comparison of mechanistic and empiric modeling approaches

Anna Osberghaus,Stefan Hepbildikler,et al.

201264 citations

Prediction uncertainty assessment of chromatography models using Bayesian inference

Till Briskot,Ferdinand Stückler,et al.

201855 citations

Model-integrated process development demonstrated on the optimization of a robotic cation exchange step

Anna Osberghaus,K. Drechsel,et al.

201253 citations

Modeling of complex antibody elution behavior under high protein load densities in ion exchange chromatography using an asymmetric activity coefficient

Thiemo Huuk,Tobias Hahn,et al.

201636 citations

Investigation of fouling mechanisms of virus filters during the filtration of protein solutions using a high throughput filtration screening device

Marc Bieberbach,Peter Kosiol,et al.

201931 citations

Calibration‐free inverse modeling of ion‐exchange chromatography in industrial antibody purification

Tobias Hahn,Thiemo Huuk,et al.

201531 citations

Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences

Jon Coffman,Bruno Marques,et al.

202017 citations