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Roberto Zoncu | Researchclopedia

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Roberto Zoncu

University of California, Berkeley ORCID

122

Works

27,071

Citations

49

h-index

66

i10-index

Research Topics

Cellular transport and secretion Autophagy in Disease and Therapy Calcium signaling and nucleotide metabolism

Affiliations

QB32016–2025

Broad Institute2011–2015

University of Pisa2000–2001

Howard Hughes Medical Institute2002–2015

Berkeley College2022–2024

Top Works

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu,Alejo Efeyan,et al.

20103,931 citations

PI3K/AKT/mTOR signaling in cancer

Lysosomal Storage Disorders Research

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker,Joseph M. Hendricks,et al.

20193,427 citations

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak,Liron Bar‐Peled,et al.

20102,397 citations

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre,Roberto Zoncu,et al.

20121,890 citations

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H <sup>+</sup> -ATPase

Roberto Zoncu,Liron Bar‐Peled,et al.

20111,593 citations

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

Liron Bar‐Peled,Lawrence D. Schweitzer,et al.

2012889 citations

The lysosome as a cellular centre for signalling, metabolism and quality control

Rosalie Lawrence,Roberto Zoncu

2018885 citations

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Shuyu Wang,Zhi-Yang Tsun,et al.

2015810 citations

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

Rushika M. Perera,Svetlana Stoykova,et al.

2015783 citations