Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

James J. Champoux | Researchclopedia

Back to researchers

James J. Champoux

University of Washington

132

Works

12,419

Citations

53

h-index

112

i10-index

Research Topics

Cancer therapeutics and mechanisms DNA and Nucleic Acid Chemistry HIV Research and Treatment

Affiliations

Salk Institute for Biological Studies1972–1974

Howard Hughes Medical Institute1996–2004

University of Washington1975–2013

University of California San Diego1974–1974

Stanford Synchrotron Radiation Lightsource1998–1998

Top Works

DNA Topoisomerases: Structure, Function, and Mechanism

James J. Champoux

20012,696 citations

HIV/AIDS drug development and treatment

Bioactive Compounds and Antitumor Agents

Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

Matthew R. Redinbo,Lance Stewart,et al.

1998874 citations

A Model for the Mechanism of Human Topoisomerase I

Lance Stewart,Matthew R. Redinbo,et al.

1998699 citations

DNA topoisomerase I is involved in both repression and activation of transcription

Alejandro Merino,Knut Madden,et al.

1993379 citations

An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication

James J. Champoux,Renato Dulbecco

1972339 citations

The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

Heidrun Interthal,Jeffrey J. Pouliot,et al.

2001285 citations

Human DNA topoisomerase I: relaxation, roles, and damage control

John B. Leppard,James J. Champoux

2005227 citations

Deletions affecting the transposition of an antibiotic resistance gene.

Fred Heffron,Patricia A. Bedinger,et al.

1977219 citations

Human Tdp1 Cleaves a Broad Spectrum of Substrates, Including Phosphoamide Linkages

Heidrun Interthal,Hong Jing Chen,et al.

2005218 citations