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James P. Broughton | Researchclopedia

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James P. Broughton

Mammoth Biosciences (United States)ORCID

25

Works

6,039

Citations

14

h-index

15

i10-index

Research Topics

CRISPR and Genetic Engineering RNA Research and Splicing RNA modifications and cancer

Affiliations

National Institutes of Health2011–2011

University of California, San Francisco2020–2020

UC San Diego Health System2016–2016

University of California, San Diego2013–2018

Dynamic Imaging (United Kingdom)2020–2020

Top Works

CRISPR–Cas12-based detection of SARS-CoV-2

James P. Broughton,Xianding Deng,et al.

20202,720 citations

MicroRNA in disease regulation

SARS-CoV-2 detection and testing

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

Huabing Li,Jiyu Tong,et al.

20171,026 citations

N6-Methyladenosine Modification Controls Circular RNA Immunity

Y. Grace Chen,Robert Chen,et al.

2019565 citations

Pairing beyond the Seed Supports MicroRNA Targeting Specificity

James P. Broughton,Michael Lovci,et al.

2016497 citations

m6A mRNA methylation sustains Treg suppressive functions

Jiyu Tong,Guangchao Cao,et al.

2018366 citations

RNA structure maps across mammalian cellular compartments

Lei Sun,Furqan M. Fazal,et al.

2019254 citations

Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay

James P. Broughton,Xianding Deng,et al.

2020152 citations

TRIM79α, an Interferon-Stimulated Gene Product, Restricts Tick-Borne Encephalitis Virus Replication by Degrading the Viral RNA Polymerase

R. Travis Taylor,Kirk J. Lubick,et al.

2011104 citations

The m <sup>6</sup> A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor

Yiren Xiao,Kaushik N. Thakkar,et al.

2020100 citations