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Ji-Hu Zhang | Researchclopedia

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Ji-Hu Zhang

Novartis (China)

41

Works

10,077

Citations

19

h-index

27

i10-index

Research Topics

Computational Drug Discovery Methods Receptor Mechanisms and Signaling Protein Tyrosine Phosphatases

Affiliations

Maxygen (United States)1997–1997

California Institute of Technology1994–1994

Novartis (Switzerland)2010–2013

DuPont (United States)1998–2000

Bristol-Myers Squibb (Germany)2002–2002

Top Works

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang,Thomas D.Y. Chung,et al.

19996,903 citations

Epigenetics and DNA Methylation

Mass Spectrometry Techniques and Applications

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen,Matthew J. LaMarche,et al.

2016910 citations

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

Wei Qi,Homan Chan,et al.

2012543 citations

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet,Christine Hiu-Tung Chen,et al.

2016287 citations

Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening

Ji-Hu Zhang,Glenn Dawes,et al.

1997275 citations

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche,Michael Acker,et al.

2020210 citations

Small-molecule WNK inhibition regulates cardiovascular and renal function

Ken Yamada,Hyi-Man Park,et al.

2016165 citations

Mass Spectrometric Techniques for Label-free High-Throughput Screening in Drug Discovery

Thomas P. Roddy,Christopher R. Horvath,et al.

200786 citations

Metal-mediated protein stabilization

Frances H. Arnold,Ji-Hu Zhang

199485 citations