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John F. Hancock | Researchclopedia

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John F. Hancock

The University of Texas MD Anderson Cancer Center ORCID

282

Works

27,448

Citations

84

h-index

186

i10-index

Research Topics

Protein Kinase Regulation and GTPase Signaling Cellular transport and secretion Lipid Membrane Structure and Behavior

Affiliations

Fauna and Flora International1983–1983

Translational Genomics Research Institute2021–2021

Centre National de la Recherche Scientifique1994–1994

University of Helsinki2010–2010

Texas Medical Center2013–2016

Top Works

All ras proteins are polyisoprenylated but only some are palmitoylated

John F. Hancock,Anthony I. Magee,et al.

19891,815 citations

Caveolin-1 and cellular processes

PI3K/AKT/mTOR signaling in cancer

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

John F. Hancock,Hugh Paterson,et al.

19901,066 citations

Activation of Raf as a Result of Recruitment to the Plasma Membrane

David Stokoe,Susan G. Macdonald,et al.

1994985 citations

Ras proteins: different signals from different locations

John F. Hancock

2003855 citations

Lipid rafts: contentious only from simplistic standpoints

John F. Hancock

2006782 citations

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

Michelle M. Hill,Michele Bastiani,et al.

2008746 citations

Direct visualization of Ras proteins in spatially distinct cell surface microdomains

Ian A. Prior,Cornelia Muncke,et al.

2003732 citations

Signalling ballet in space and time

Boris Ν. Kholodenko,John F. Hancock,et al.

2010618 citations

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

Ian A. Prior,Angus Harding,et al.

2001522 citations