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Shikshya Shrestha | Researchclopedia

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Shikshya Shrestha

The University of Sydney ORCID

45

Works

9,321

Citations

9

h-index

9

i10-index

Research Topics

Colorectal Cancer Treatments and Studies Biochemical and Molecular Research Pancreatic and Hepatic Oncology Research

Affiliations

Brigham and Women's Hospital2019–2024

The University of Sydney2025–2025

Mayo Clinic2015–2018

Harvard University2019–2024

Pokhara University2022–2022

Top Works

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shikshya Shrestha,Steven M. Offer

20168,955 citations

Epigenetics and DNA Methylation

Cancer, Hypoxia, and Metabolism

Gene‐Specific Variant Classifier (DPYD‐Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase

Shikshya Shrestha,Cheng Zhang,et al.

201878 citations

Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity

Qian Nie,Shikshya Shrestha,et al.

201764 citations

Decreased malaria morbidity in the Tharu people compared to sympatric populations in Nepal

L. Terrenato,Shikshya Shrestha,et al.

198850 citations

Novel Deleterious Dihydropyrimidine Dehydrogenase Variants May Contribute to 5‐Fluorouracil Sensitivity in an East African Population

Tarig Elraiyah,Calvin R. Jerde,et al.

201646 citations

Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter

Rentian Wu,Qian Nie,et al.

201624 citations

Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways

Benjamin Stump,Shikshya Shrestha,et al.

201914 citations

Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD

Jonathan E. Knikman,Qinglian Zhai,et al.

202411 citations

ETV2 regulates PARP-1 binding protein to induce ER stress–mediated death in tuberin-deficient cells

Shikshya Shrestha,Anthony M. Lamattina,et al.

202210 citations