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Siddharth Kaul | Researchclopedia

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Siddharth Kaul

14

Works

3,206

Citations

11

h-index

11

i10-index

Research Topics

Parkinson's Disease Mechanisms and Treatments Neuroscience and Neuropharmacology Research Nerve injury and regeneration

Affiliations

Iowa State University2002–2008

Southern Illinois University School of Medicine2013–2014

Top Works

Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase Cδ Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl

Vellareddy Anantharam,Masashi Kitazawa,et al.

2002219 citations

Alzheimer's disease research and treatments

Cell death mechanisms and regulation

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP<sup>+</sup>)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

Siddharth Kaul,Arthi Kanthasamy,et al.

2003165 citations

Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells

Vellareddy Anantharam,Siddharth Kaul,et al.

2007116 citations

Tyrosine Phosphorylation Regulates the Proteolytic Activation of Protein Kinase Cδ in Dopaminergic Neuronal Cells

Siddharth Kaul,Vellareddy Anantharam,et al.

2005114 citations

Suppression of caspase-3-dependent proteolytic activation of protein kinase Cδ by small interfering RNA prevents MPP+-induced dopaminergic degeneration

Yongjie Yang,Siddharth Kaul,et al.

200472 citations

A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCδ) protects against dopaminergic neuronal degeneration in Parkinson’s disease models

Anumantha G. Kanthasamy,Vellareddy Anantharam,et al.

200671 citations

Wild-type α-synuclein interacts with pro-apoptotic proteins PKCδ and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death

Siddharth Kaul,Vellareddy Anantharam,et al.

200569 citations

Chronic Low‐Dose Oxidative Stress Induces Caspase‐3‐Dependent PKCδ Proteolytic Activation and Apoptosis in a Cell Culture Model of Dopaminergic Neurodegeneration

Martha L. Carvour,Chunjuan Song,et al.

200851 citations

Proteolytic Activation of Proapoptotic Kinase PKCδ Is Regulated by Overexpression of Bcl‐2

Arthi Kanthasamy,Arthi Kanthasamy,et al.

200337 citations