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Brian J. Long | Researchclopedia

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Brian J. Long

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID

132

Works

4,608

Citations

33

h-index

47

i10-index

Research Topics

Estrogen and related hormone effects Cancer Immunotherapy and Biomarkers Hippo pathway signaling and YAP/TAZ

Affiliations

Tongji University2024–2025

Queen's University Belfast1994–1994

University of Maryland, Baltimore1998–2006

Rush University Medical Center1993–1993

Merck & Co., Inc., Rahway, NJ, USA (United States)2011–2026

Top Works

Discovery of a Novel ERK Inhibitor with Activity in Models of Acquired Resistance to BRAF and MEK Inhibitors

Erick J. Morris,Sharda Jha,et al.

2013678 citations

interferon and immune responses

Melanoma and MAPK Pathways

An orally available non-nucleotide STING agonist with antitumor activity

Bo‐Sheng Pan,Samanthi A. Perera,et al.

2020626 citations

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

Tikvah K. Hayes,Nicole F. Neel,et al.

2015271 citations

Preclinical Evaluation of the WEE1 Inhibitor MK-1775 as Single-Agent Anticancer Therapy

Amy D. Guertin,Jing Li,et al.

2013170 citations

Signaling pathways of apoptosis activated by aromatase inhibitors and antiestrogens.

Apinya Thiantanawat,Brian J. Long,et al.

2003162 citations

The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling

Andrea Basso,Asra Mirza,et al.

2005161 citations

Aromatase and COX-2 expression in human breast cancers

A. Brodie,Qing Lü,et al.

2001150 citations

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

Stergios J. Moschos,Ryan J. Sullivan,et al.

2018146 citations

Activation of Mitogen-Activated Protein Kinase in Xenografts and Cells during Prolonged Treatment with Aromatase Inhibitor Letrozole

Danijela Jelovac,Gauri Sabnis,et al.

2005146 citations