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René de Waal Malefyt | Researchclopedia

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René de Waal Malefyt

Synthego (United States)ORCID

200

Works

52,310

Citations

78

h-index

136

i10-index

Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Immunotherapy and Immune Responses

Affiliations

University of Siena2000–2000

Université Paris-Sud1992–1992

Leiden University2004–2004

Tufts University1996–1996

Merck & Co., Inc., Rahway, NJ, USA (United States)2010–2024

Top Works

Interleukin-10 and the Interleukin-10 Receptor

Kevin W. Moore,René de Waal Malefyt,et al.

20016,658 citations

Cytokine Signaling Pathways and Interactions

Asthma and respiratory diseases

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

René de Waal Malefyt,J S Abrams,et al.

19913,803 citations

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Birgit Oppmann,Robin Lesley,et al.

20002,788 citations

Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

Vassili Soumelis,Pedro A. Reche,et al.

20022,135 citations

Development, cytokine profile and function of human interleukin 17–producing helper T cells

Nicholas J. Wilson,Katia Boniface,et al.

20072,001 citations

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt,John B.A.G. Haanen,et al.

19911,947 citations

Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

Norimitsu Kadowaki,Stephen Ho,et al.

20011,932 citations

Kevin W. Moore,Anne O’Garra,et al.

19931,871 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

Marie‐Clotilde Rissoan,Vassili Soumelis,et al.

19991,851 citations