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James Brugarolas | Researchclopedia

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James Brugarolas

Texas Oncology ORCID

590

Works

18,066

Citations

64

h-index

161

i10-index

Research Topics

Renal cell carcinoma treatment Renal and related cancers Cancer Genomics and Diagnostics

Affiliations

Ontario Institute for Cancer Research2018–2018

Tufts University1998–1998

Brigham and Women's Hospital2004–2004

Novartis (Switzerland)2017–2017

Cleveland Clinic2012–2013

Top Works

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas,Kui Lei,et al.

20041,367 citations

Cancer, Hypoxia, and Metabolism

Ferroptosis and cancer prognosis

Radiation-induced cell cycle arrest compromised by p21 deficiency

James Brugarolas,Chitra Chandrasekaran,et al.

19951,240 citations

BAP1 loss defines a new class of renal cell carcinoma

Samuel Peña‐Llopis,Silvia Vega-Rubín-de-Celis,et al.

2012982 citations

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Pradip K. Majumder,Phillip G. Febbo,et al.

2004956 citations

Targeting renal cell carcinoma with a HIF-2 antagonist

Wenfang Chen,Haley Hill,et al.

2016705 citations

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

James Brugarolas,Francisca Vázquez,et al.

2003525 citations

The complex relationship between <scp>TFEB</scp> transcription factor phosphorylation and subcellular localization

Rosa Puertollano,Shawn M. Ferguson,et al.

2018509 citations

Regulation of TFEB and V-ATPases by mTORC1

Samuel Peña‐Llopis,Silvia Vega-Rubín-de-Celis,et al.

2011456 citations

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

Payal Kapur,Samuel Peña‐Llopis,et al.

2013452 citations