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Larry M. Karnitz | Researchclopedia

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Larry M. Karnitz

172

Works

9,400

Citations

50

h-index

79

i10-index

Research Topics

DNA Repair Mechanisms PARP inhibition in cancer therapy Ovarian cancer diagnosis and treatment

Affiliations

University of Minnesota1984–1984

Mayo Clinic1991–2026

Cancer Research Institute1999–1999

Duke University2000–2000

New York Medical College2015–2015

Top Works

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Jann N. Sarkaria,Ericka C. Busby,et al.

19991,036 citations

Acute Myeloid Leukemia Research

Microtubule and mitosis dynamics

A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.

A Sekulić,Christine C. Hudson,et al.

2000716 citations

The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1

Sinny Delacroix,Jill M. Wagner,et al.

2007460 citations

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Bradley T. Scroggins,Kenneth Robzyk,et al.

2007408 citations

Dial 9–1–1 for DNA damage: the Rad9–Hus1–Rad1 (9–1–1) clamp complex

Edgardo R. Parrilla-Castellar,Sonnet J.H. Arlander,et al.

2004337 citations

Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.

J. Paul Secrist,L A Burns,et al.

1993320 citations

The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.

Ericka C. Busby,Dru F. Leistritz,et al.

2000316 citations

Molecular Pathways: Targeting ATR in Cancer Therapy

Larry M. Karnitz,Lee Zou

2015272 citations

ATR Inhibition Broadly Sensitizes Ovarian Cancer Cells to Chemotherapy Independent of BRCA Status

Catherine J. Huntoon,Karen S. Flatten,et al.

2013208 citations