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Bryan Laffitte | Researchclopedia

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Bryan Laffitte

Genomics Institute of the Novartis Research Foundation

48

Works

9,985

Citations

30

h-index

35

i10-index

Research Topics

Cholesterol and Lipid Metabolism Peroxisome Proliferator-Activated Receptors Drug Transport and Resistance Mechanisms

Affiliations

Genomics Institute of the Novartis Research Foundation2003–2020

Research Triangle Park Foundation2004–2008

Howard Hughes Medical Institute2000–2004

North Carolina State University2009–2020

University of California, Los Angeles2000–2004

Top Works

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

Ajay Chawla,William A. Boisvert,et al.

20011,326 citations

Pancreatic function and diabetes

Cancer, Lipids, and Metabolism

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

Sean B. Joseph,Antonio Castrillo,et al.

20031,133 citations

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

Asha Venkateswaran,Bryan Laffitte,et al.

2000991 citations

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

Sean B. Joseph,Elaine McKilligin,et al.

2002938 citations

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

Sean B. Joseph,Bryan Laffitte,et al.

2002760 citations

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

Bryan Laffitte,Joyce J. Repa,et al.

2001661 citations

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

Bryan Laffitte,Lily C. Chao,et al.

2003494 citations

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

Rajendra K. Tangirala,Eric D. Bischoff,et al.

2002436 citations

Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids

Heidi R. Kast-Woelbern,Catherine Nguyen,et al.

2001329 citations