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E. Jon Jacobsen | Researchclopedia

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E. Jon Jacobsen

Confluence Life Sciences (United States)

71

Works

3,153

Citations

29

h-index

46

i10-index

Research Topics

Nicotinic Acetylcholine Receptors Study Asymmetric Synthesis and Catalysis Chemical synthesis and alkaloids

Affiliations

University of Geneva1986–1986

Pfizer (United States)2006–2023

Urbana University1993–1993

University of California, Irvine1982–1988

Analytical Services1997–1997

Top Works

Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.

J. Mark Braughler,Jeffery F. Pregenzer,et al.

1987469 citations

Phenothiazines and Benzothiazines Synthesis and Activities

Neuroscience and Neuropharmacology Research

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Jill Chrencik,Akshay Patny,et al.

2010224 citations

Salen-Manganese Complexes Are Superoxide Dismutase-Mimics

Michel Baudry,S. Etienne,et al.

1993208 citations

Discovery of<i>N</i>-[(3<i>R</i>)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-<i>c</i>]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia: Synthesis and Structure−Activity Relationship

Donn G. Wishka,Daniel P. Walker,et al.

2006189 citations

U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia.

Edward D. Hall,J. Mark Braughler,et al.

1991153 citations

The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia

J. Mark Braughler,Edward D. Hall,et al.

1989128 citations

The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes

John E. Tavis,Xiaohong Cheng,et al.

2013109 citations

Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals

Chun Wang,Susan L. Hockerman,et al.

201899 citations

Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Daniel P. Walker,Donn G. Wishka,et al.

200694 citations