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Karin Pelka | Researchclopedia

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Karin Pelka

Broad Institute ORCID

67

Works

5,145

Citations

24

h-index

31

i10-index

Research Topics

Single-cell and spatial transcriptomics Cancer Immunotherapy and Biomarkers Immune Response and Inflammation

Affiliations

Broad Institute2017–2025

Uppsala University2013–2013

Gladstone Institutes2022–2025

University of Bonn1972–2015

Harvard University2019–2025

Top Works

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

Anette Christ,Patrick Günther,et al.

2018998 citations

Cancer Genomics and Diagnostics

Immunotherapy and Immune Responses

Spatially organized multicellular immune hubs in human colorectal cancer

Karin Pelka,Matan Hofree,et al.

2021754 citations

Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics

Leif S. Ludwig,Caleb A. Lareau,et al.

2019546 citations

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Bob Chen,Cherie’ R. Scurrah,et al.

2021326 citations

Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions

Michael R. Filbin,Arnav Mehta,et al.

2021302 citations

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling

Caleb A. Lareau,Leif S. Ludwig,et al.

2020301 citations

Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

Sarah E. Johnstone,Alejandro Reyes,et al.

2020249 citations

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

Cherilyn M. Sirois,Tengchuan Jin,et al.

2013218 citations

Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial

Jun Tian,Jonathan Chen,et al.

2023173 citations