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Andrew Mancini | Researchclopedia

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Andrew Mancini

Molecular Oncology (United States)

23

Works

1,185

Citations

8

h-index

8

i10-index

Research Topics

Telomeres, Telomerase, and Senescence Glioma Diagnosis and Treatment Cancer Research and Treatments

Affiliations

University of California, San Francisco2015–2023

Molecular Oncology (United States)2022–2025

Neurological Surgery2015–2021

University of San Francisco2023–2023

Top Works

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Robert J.A. Bell,H. Tomas Rube,et al.

2015568 citations

Cancer Cells and Metastasis

Virus-based gene therapy research

Understanding TERT Promoter Mutations: A Common Path to Immortality

Robert J.A. Bell,H. Tomas Rube,et al.

2016297 citations

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Andrew Mancini,Ana Xavier‐Magalhães,et al.

2018148 citations

Mutant IDH1 Expression Drives <i>TERT</i> Promoter Reactivation as Part of the Cellular Transformation Process

Shigeo Ohba,Joydeep Mukherjee,et al.

201661 citations

Cancer-specific loss of <i>TERT</i> activation sensitizes glioblastoma to DNA damage

Alexandra M. Amen,Christof Fellmann,et al.

202151 citations

Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis

Antonina V. Kurtova,Melanie Heinlein,et al.

202231 citations

Crypt density and recruited enhancers underlie intestinal tumour initiation

Liam T. Gaynor,Harshabad Singh,et al.

202515 citations

Ligand-activated EGFR/MAPK signaling but not PI3K, are key resistance mechanisms to EGFR-therapy in colorectal cancer

Xueping Qu,Habib Hamidi,et al.

202512 citations

Abstract B12: GABP selectively binds and activates the mutant TERT promoter across multiple cancer types

Robert J.A. Bell,H. Tomas Rube,et al.

20153 citations