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Ruth M. Kluck | Researchclopedia

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Ruth M. Kluck

The University of Melbourne ORCID

90

Works

14,790

Citations

45

h-index

64

i10-index

Research Topics

Cell death mechanisms and regulation Mitochondrial Function and Pathology RNA Interference and Gene Delivery

Affiliations

Scripps Research Institute1999–1999

La Jolla Institute for Immunology1997–2001

The Royal Melbourne Hospital2016–2016

National University of Ireland, Maynooth1999–1999

University of Queensland1985–1993

Top Works

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck,Ella Bossy‐Wetzel,et al.

19974,727 citations

ATP Synthase and ATPases Research

Autophagy in Disease and Therapy

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

Elizabeth A. Slee,Mary T. Harte,et al.

19991,926 citations

Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

Simon N. Willis,Jamie I. Fletcher,et al.

20071,100 citations

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

Peter E. Czabotar,Dana Westphal,et al.

2013566 citations

Molecular biology of Bax and Bak activation and action

Dana Westphal,Grant Dewson,et al.

2010513 citations

Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis

Dana Westphal,Ruth M. Kluck,et al.

2013427 citations

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system

1997384 citations

Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

Grant Dewson,Ruth M. Kluck

2009351 citations

To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions

Grant Dewson,Tobias Kratina,et al.

2008335 citations