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Derek J. Parks | Researchclopedia

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Derek J. Parks

49

Works

11,939

Citations

34

h-index

43

i10-index

Research Topics

Drug Transport and Resistance Mechanisms Estrogen and related hormone effects Peroxisome Proliferator-Activated Receptors

Affiliations

Dartmouth College2001–2001

Research Triangle Park Foundation1994–2015

Target (United States)2009–2009

Colorado School of Mines2009–2009

University of Perugia2002–2006

Top Works

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks,Steven G. Blanchard,et al.

19992,231 citations

Cholesterol and Lipid Metabolism

Pharmacogenetics and Drug Metabolism

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H. Eric Xu,Millard H. Lambert,et al.

19991,159 citations

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Randy K. Bledsoe,Valerie G. Montana,et al.

2002813 citations

Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands

Linda B. Moore,Derek J. Parks,et al.

2000809 citations

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Roberto Pellicciari,Stefano Fiorucci,et al.

2002726 citations

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

Lei Yin,Nan Wu,et al.

2007711 citations

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

H. Eric Xu,Thomas B. Stanley,et al.

2002610 citations

Functional Consequences of Cysteine Modification in the Ligand Binding Sites of Peroxisome Proliferator Activated Receptors by GW9662

Lisa M. Leesnitzer,Derek J. Parks,et al.

2002558 citations

Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR

Patrick Maloney,Derek J. Parks,et al.

2000521 citations