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Lorna A. Farrelly | Researchclopedia

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Lorna A. Farrelly

Regeneron (United States)ORCID

25

Works

1,351

Citations

12

h-index

12

i10-index

Research Topics

Epigenetics and DNA Methylation Genetics and Neurodevelopmental Disorders Stress Responses and Cortisol

Affiliations

Allen Institute for Brain Science2016–2024

Royal College of Surgeons in Ireland2014–2017

Hess (United States)2021–2021

Regeneron (United States)2023–2025

Princeton University2024–2024

Top Works

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3

Lorna A. Farrelly,Robert E. Thompson,et al.

2019454 citations

Genomics and Chromatin Dynamics

Tryptophan and brain disorders

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity

Ian Maze,Wendy Wenderski,et al.

2015315 citations

Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking

Ashley E. Lepack,Craig Werner,et al.

2020226 citations

Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout

Shuai Zhao,Kelly N. Chuh,et al.

202176 citations

Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior

Ashley E. Lepack,Rosemary C. Bagot,et al.

201665 citations

Maternal Immune Activation Induces Changes in Myelin and Metabolic Proteins, Some of Which Can Be Prevented with Risperidone in Adolescence

Lorna A. Farrelly,Melanie Föcking,et al.

201539 citations

Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior

Amni Al-Kachak,G. Salvo,et al.

202436 citations

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

Lorna A. Farrelly,Shuangping Zheng,et al.

202234 citations

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Sasha L. Fulton,Wendy Wenderski,et al.

202225 citations