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Leroy F. Liu | Researchclopedia

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Leroy F. Liu

Dalian Medical University ORCID

379

Works

46,225

Citations

99

h-index

269

i10-index

Research Topics

Cancer therapeutics and mechanisms Bioactive Compounds and Antitumor Agents DNA and Nucleic Acid Chemistry

Affiliations

Rutgers, The State University of New Jersey1993–2014

Supélec1987–1987

Tri-Service General Hospital2012–2012

Salk Institute for Biological Studies1991–1991

St. Jude Children's Research Hospital1999–2005

Top Works

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang,Robert Hertzberg,et al.

19852,340 citations

DNA Repair Mechanisms

Synthesis and Biological Evaluation

Supercoiling of the DNA template during transcription.

Leroy F. Liu,J C Wang

19871,978 citations

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

Sui Zhang,Xiaobing Liu,et al.

20121,904 citations

DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGS

19891,800 citations

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey,Thomas C. Rowe,et al.

19841,531 citations

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Qian Li,Yu Huang,et al.

20121,347 citations

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.

Y H Hsiang,M G Lihou,et al.

19891,036 citations

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

K M Tewey,G L Chen,et al.

1984887 citations

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.

Yaw Huei Hsiang,Leroy F. Liu

1988844 citations