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Keiran S.M. Smalley | Researchclopedia

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Keiran S.M. Smalley

Moffitt Cancer Center ORCID

530

Works

20,146

Citations

63

h-index

165

i10-index

Research Topics

Melanoma and MAPK Pathways Brain Metastases and Treatment Cutaneous Melanoma Detection and Management

Affiliations

The Wistar Institute2003–2023

Florida State University2014–2023

Queens College, CUNY2024–2024

University of Copenhagen2023–2023

Florida A&M University - Florida State University College of Engineering2023–2023

Top Works

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai,John Tayu Lee,et al.

20081,341 citations

CAR-T cell therapy research

Cancer Mechanisms and Therapy

PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression

Kim H.T. Paraiso,Yun Xiang,et al.

2011546 citations

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

Keiran S.M. Smalley,Nikolas K. Haass,et al.

2006459 citations

Adhesion, migration and communication in melanocytes and melanoma

Nikolas K. Haass,Keiran S.M. Smalley,et al.

2005379 citations

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

Keiran S.M. Smalley

2003327 citations

Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy

Kim H.T. Paraiso,Inna V. Fedorenko,et al.

2010312 citations

LIFE ISN'T FLAT: TAKING CANCER BIOLOGY TO THE NEXT DIMENSION

Keiran S.M. Smalley,Mercedes Lioni,et al.

2006300 citations

Increased cyclin D1 expression can mediate BRAF inhibitor resistance in <i>BRAF</i> V600E–mutated melanomas

Keiran S.M. Smalley,Mercedes Lioni,et al.

2008293 citations

Rewired ERK-JNK Signaling Pathways in Melanoma

Pablo Lopez‐Bergami,Conway C. Huang,et al.

2007286 citations