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Xin Yu | Researchclopedia

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Xin Yu

Shandong University ORCID

98

Works

6,998

Citations

30

h-index

57

i10-index

Research Topics

Alzheimer's disease research and treatments Cancer-related molecular mechanisms research Genetic Neurodegenerative Diseases

Affiliations

Mayo Clinic2010–2010

Nanchang University2013–2024

Shandong University2025–2025

Stockholm University2012–2015

China Pharmaceutical University2017–2017

Top Works

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Karen Duff,Chris Eckman,et al.

19961,449 citations

Mitochondrial Function and Pathology

Amyotrophic Lateral Sclerosis Research

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Leigh A. Holcomb,Marcia N. Gordon,et al.

19981,398 citations

Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice

Ya-Fei Xu,Tania F. Gendron,et al.

2010569 citations

Characterization of Pathology in Transgenic Mice Over-Expressing Human Genomic and cDNA Tau Transgenes

Karen Duff,Heather Knight,et al.

2000310 citations

A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling

Harald Steiner,Karen Duff,et al.

1999307 citations

Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging

Zeshan Ahmed,Sheng Hong,et al.

2010303 citations

Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter

Yasuji Matsuoka,Miquel Vila,et al.

2001278 citations

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

Heather L. Melrose,Justus C. Dächsel,et al.

2010277 citations

Cytokines Regulate Gelatinase A and B (Matrix Metalloproteinase 2 and 9) Activity in Cultured Rat Astrocytes

Paul E. Gottschall,Xin Yu

1995191 citations