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Lena F. Burbulla | Researchclopedia

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Lena F. Burbulla

Munich Cluster for Systems Neurology ORCID

50

Works

8,114

Citations

26

h-index

34

i10-index

Research Topics

Parkinson's Disease Mechanisms and Treatments Lysosomal Storage Disorders Research Neurological diseases and metabolism

Affiliations

Université Paris-Sud2022–2022

Northwestern University2016–2024

Harvard University2016–2017

Inserm2022–2024

Université de Versailles Saint-Quentin-en-Yvelines2022–2024

Top Works

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

Lena F. Burbulla,Pingping Song,et al.

2017849 citations

Mitochondrial Function and Pathology

Autophagy in Disease and Therapy

Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression

Peter Reinhardt,Benjamin Schmid,et al.

2013507 citations

Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease

Chung-Han Hsieh,Atossa Shaltouki,et al.

2016463 citations

Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1

Guido Krebiehl,Sabine Ruckerbauer,et al.

2010377 citations

Activation of -Glucocerebrosidase Reduces Pathological -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons

Joseph R. Mazzulli,Friederike Zunke,et al.

2016274 citations

Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain

Steven M. Graves,Zhong Xie,et al.

2019179 citations

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

Lena F. Burbulla,Carina Schelling,et al.

2010136 citations

A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease

Lena F. Burbulla,Sohee Jeon,et al.

2019105 citations

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1

Lena F. Burbulla,Julia C. Fitzgerald,et al.

201499 citations