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Dragomir B. Krastev | Researchclopedia

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Dragomir B. Krastev

Institute of Cancer Research ORCID

103

Works

3,014

Citations

18

h-index

23

i10-index

Research Topics

PARP inhibition in cancer therapy DNA Repair Mechanisms CRISPR and Genetic Engineering

Affiliations

Institute of Cancer Research2016–2026

Max Planck Society2011–2011

South-West University "Neofit Rilski"2020–2020

German Cancer Research Center2020–2021

Heidelberg University2020–2021

Top Works

The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer,Salomé Adam,et al.

2018642 citations

Sarcoma Diagnosis and Treatment

Microtubule and mitosis dynamics

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Stephen J. Pettitt,Dragomir B. Krastev,et al.

2018438 citations

Structural basis for allosteric PARP-1 retention on DNA breaks

Levani Zandarashvili,Marie-France Langelier,et al.

2020321 citations

PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer

Roman M. Chabanon,Gareth Muirhead,et al.

2018314 citations

A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia

Mikołaj Słabicki,Mirko Theis,et al.

2010195 citations

Protein Dynamics in Complex DNA Lesions

Radoslav Aleksandrov,Anton Dotchev,et al.

2018171 citations

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev,Shudong Li,et al.

2022158 citations

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Ilirjana Bajrami,Rebecca Marlow,et al.

2018130 citations

Mammalian Ino80 Mediates Double-Strand Break Repair through Its Role in DNA End Strand Resection

Anastas Gospodinov,Thomas Vaissière,et al.

2011104 citations