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Timothy A. Yap | Researchclopedia

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Timothy A. Yap

The University of Texas MD Anderson Cancer Center ORCID

1,358

Works

26,557

Citations

77

h-index

225

i10-index

Research Topics

PARP inhibition in cancer therapy interferon and immune responses Cancer Genomics and Diagnostics

Affiliations

AstraZeneca (United Kingdom)2007–2007

National Health Service2010–2014

Queen's University Belfast2011–2011

Roswell Park Comprehensive Cancer Center2007–2007

Engineering and Physical Sciences Research Council2013–2013

Top Works

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers

Peter C.C. Fong,David S. Boss,et al.

20093,610 citations

DNA Repair Mechanisms

Cancer Immunotherapy and Biomarkers

State-of-the-art strategies for targeting the DNA damage response in cancer

Patrick G. Pilié,Chad Tang,et al.

20181,179 citations

Targeting the PI3K pathway in cancer: are we making headway?

Filip Jankú,Timothy A. Yap,et al.

20181,024 citations

Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses in <i>BRCA</i> Carrier Ovarian Cancer Correlating With Platinum-Free Interval

Peter C.C. Fong,Timothy A. Yap,et al.

2010989 citations

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

Gerhardt Attard,Alison Reid,et al.

2008895 citations

Targeting DNA Repair in Cancer: Beyond PARP Inhibitors

Jessica Brown,Brent O’Carrigan,et al.

2016622 citations

PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness

Jianfeng Shen,Wei Zhao,et al.

2018575 citations

First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

Timothy A. Yap,Yan Li,et al.

2011542 citations

Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

Timothy A. Yap,Michelle D. Garrett,et al.

2008542 citations