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Diana C.J. Spierings | Researchclopedia

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Diana C.J. Spierings

University Medical Center Groningen ORCID

286

Works

7,659

Citations

44

h-index

85

i10-index

Research Topics

Cancer Genomics and Diagnostics Cancer-related Molecular Pathways Cancer, Hypoxia, and Metabolism

Affiliations

La Jolla Institute for Immunology2005–2006

St. Jude Children's Research Hospital2006–2007

University Medical Center Groningen2000–2025

University of Groningen2000–2025

Max Planck Institute for Biology of Ageing2021–2025

Top Works

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Mark Chaisson,Ashley D. Sanders,et al.

20191,027 citations

Microtubule and mitosis dynamics

Genomic variations and chromosomal abnormalities

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals

Michelle S. Levine,Björn Bakker,et al.

2017391 citations

cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers

Christy Hong,Michaël Schubert,et al.

2022345 citations

Connected to Death: The (Unexpurgated) Mitochondrial Pathway of Apoptosis

Diana C.J. Spierings,Gavin P. McStay,et al.

2005294 citations

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

Yael Cohen‐Sharir,James M. McFarland,et al.

2021285 citations

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Björn Bakker,Aaron Taudt,et al.

2016273 citations

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

Ana C.F. Bolhaqueiro,Bas Ponsioen,et al.

2019242 citations

Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

Marica Rosaria Ippolito,Valentino Martis,et al.

2021191 citations

Tissue Distribution of the Death Ligand TRAIL and Its Receptors

Diana C.J. Spierings,Elisabeth G.E. de Vries,et al.

2004180 citations