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Vamsi K. Mootha | Researchclopedia

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Vamsi K. Mootha

Broad Institute ORCID

367

Works

125,450

Citations

109

h-index

195

i10-index

Research Topics

Mitochondrial Function and Pathology Metabolism and Genetic Disorders RNA modifications and cancer

Affiliations

Broad Institute2004–2025

Boston University2013–2013

Tufts University2018–2018

Brigham and Women's Hospital2000–2004

Leeds General Infirmary2016–2016

Top Works

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian,Pablo Tamayo,et al.

200555,537 citations

ATP Synthase and ATPases Research

Adipose Tissue and Metabolism

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha,Cecilia M. Lindgren,et al.

200310,486 citations

Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

Zhidan Wu,Pere Puigserver,et al.

19994,079 citations

Metabolite profiles and the risk of developing diabetes

Thomas J. Wang,Martin G. Larson,et al.

20113,110 citations

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

David J. Pagliarini,Sarah E. Calvo,et al.

20081,989 citations

Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

Xiaohui Xie,Jun Lü,et al.

20051,896 citations

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Joshua M. Baughman,Fabiana Perocchi,et al.

20111,881 citations

MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

Sneha Rath,Rohit Sharma,et al.

20201,880 citations

mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex

John T. Cunningham,Joseph T. Rodgers,et al.

20071,481 citations