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Alex G. Therien | Researchclopedia

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Alex G. Therien

Merck & Co., Inc., Rahway, NJ, USA (United States)

63

Works

3,575

Citations

33

h-index

46

i10-index

Research Topics

Clostridium difficile and Clostridium perfringens research Inflammatory mediators and NSAID effects Ion Transport and Channel Regulation

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)2012–2024

University of Toronto2001–2004

TransCanada (Canada)2010–2010

Hospital for Sick Children2001–2004

Merck Canada Inc. (Canada)2005–2012

Top Works

Mechanisms of sodium pump regulation

Alex G. Therien,Rhoda Blostein

2000764 citations

Viral gastroenteritis research and epidemiology

Asthma and respiratory diseases

Restoring Methicillin-Resistant <i>Staphylococcus aureus</i> Susceptibility to β-Lactam Antibiotics

Christopher M. Tan,Alex G. Therien,et al.

2012244 citations

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development

Nicholas Murgolo,Alex G. Therien,et al.

2021214 citations

Tissue-specific Distribution and Modulatory Role of the γ Subunit of the Na,K-ATPase

Alex G. Therien,Rivka Goldshleger,et al.

1997144 citations

Mechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography

Peter Orth,Li Xiao,et al.

2014135 citations

Expression and Functional Role of the γ Subunit of the Na,K-ATPase in Mammalian Cells

Alex G. Therien,Steven J.D. Karlish,et al.

1999126 citations

Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease

Anthony W. Partridge,Alex G. Therien,et al.

2004107 citations

Tissue-specific Versus Isoform-specific Differences in Cation Activation Kinetics of the Na,K-ATPase

Alex G. Therien,Nestor B. Nestor,et al.

1996100 citations

MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7 H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a Selective E Prostanoid Receptor 4 Antagonist, Relieves Joint Inflammation and Pain in Rodent Models of Rheumatoid and Osteoarthritis

Patsy Clark,Steven E. Rowland,et al.

200898 citations