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Jana M. Ellegast | Researchclopedia

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Jana M. Ellegast

Broad Institute ORCID

67

Works

3,029

Citations

13

h-index

13

i10-index

Research Topics

Acute Myeloid Leukemia Research interferon and immune responses Protein Degradation and Inhibitors

Affiliations

Broad Institute2021–2026

Boston Children's Hospital2017–2023

University of Bonn2006–2006

Harvard University2018–2023

Universität Ulm2010–2012

Top Works

5'-Triphosphate RNA Is the Ligand for RIG-I

Veit Hornung,Jana M. Ellegast,et al.

20062,410 citations

RNA Interference and Gene Delivery

Mosquito-borne diseases and control

Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice

Yasuyuki Saito,Jana M. Ellegast,et al.

201683 citations

Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33

Ninel Azoitei,Christopher M. Hoffmann,et al.

201278 citations

RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia

Saskia Rudat,Anja Pfaus,et al.

201866 citations

Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor

Blandine Roux,Camille Vaganay,et al.

202153 citations

Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2

Jonathan R. LaRochelle,Michelle Fodor,et al.

201752 citations

inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice

Jana M. Ellegast,Philipp J. Rauch,et al.

201645 citations

MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia

Philipp J. Rauch,Jana M. Ellegast,et al.

201645 citations

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma

Diana Lu,Jana M. Ellegast,et al.

202341 citations