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B.A. Appleton | Researchclopedia

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B.A. Appleton

91

Works

3,170

Citations

26

h-index

30

i10-index

Research Topics

Melanoma and MAPK Pathways Neurological diseases and metabolism Protein Kinase Regulation and GTPase Signaling

Affiliations

Novartis (Switzerland)2011–2015

Harvard University2003–2005

Scripps Institution of Oceanography2018–2018

University of Toronto2009–2009

Genesys (United States)2009–2009

Top Works

A Specificity Map for the PDZ Domain Family

Raffi Tonikian,Yingnan Zhang,et al.

2008489 citations

Synthesis and biological activity

Cancer Mechanisms and Therapy

Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site

Jenny Boström,Shang‐Fan Yu,et al.

2009363 citations

Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding

B.A. Appleton,Ping Wu,et al.

2007207 citations

Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors—Insight into Heterotrimeric IL-1 Signaling Complexes

Andreas Lingel,Thomas Weiß,et al.

2009206 citations

Comprehensive Analysis of the Factors Contributing to the Stability and Solubility of Autonomous Human VH Domains

Pierre A. Barthelemy,Helga Raab,et al.

2007175 citations

Inhibition of Wnt signaling by Dishevelled PDZ peptides

Yingnan Zhang,B.A. Appleton,et al.

2009160 citations

A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients

Ralph Tiedt,Elisa Degenkolbe,et al.

2011133 citations

GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis

Jonathan M. Goodwin,Ward G. Walkup,et al.

2021122 citations

The Crystal Structure of Murine Coronin-1: A Regulator of Actin Cytoskeletal Dynamics in Lymphocytes

B.A. Appleton,Ping Wu,et al.

2006119 citations