Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

Tadas S. Vasaitis | Researchclopedia

Back to researchers

Tadas S. Vasaitis

University of Maryland Eastern Shore

26

Works

1,430

Citations

19

h-index

20

i10-index

Research Topics

Prostate Cancer Treatment and Research Estrogen and related hormone effects Hormonal and reproductive studies

Affiliations

University of Maryland, Baltimore2003–2014

University of Maryland Eastern Shore2010–2025

U-M Rogel Cancer Center2008–2008

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center2006–2006

Top Works

Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens: Synthesis, in Vitro Biological Activity, Pharmacokinetics, and Antitumor Activity in the LAPC4 Human Prostate Cancer Xenograft Model

Venkatesh Handratta,Tadas S. Vasaitis,et al.

2005246 citations

Pharmacogenetics and Drug Metabolism

PI3K/AKT/mTOR signaling in cancer

CYP17 inhibitors for prostate cancer therapy

Tadas S. Vasaitis,Robert D. Bruno,et al.

2010207 citations

Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases

Vincent C.O. Njar,Lalji K. Gediya,et al.

2006146 citations

Androgen receptor inactivation contributes to antitumor efficacy of 17α-hydroxylase/17,20-lyase inhibitor 3β-hydroxy-17-(1<i>H</i>-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer

Tadas S. Vasaitis,Aashvini Belosay,et al.

2008134 citations

Systematic Structure Modifications of Multitarget Prostate Cancer Drug Candidate Galeterone To Produce Novel Androgen Receptor Down-Regulating Agents as an Approach to Treatment of Advanced Prostate Cancer

Puranik Purushottamachar,Abhijit M. Godbole,et al.

2013103 citations

Three Dimensional Pharmacophore Modeling of Human CYP17 Inhibitors. Potential Agents for Prostate Cancer Therapy

Omoshile Clement,C. M. Freeman,et al.

200383 citations

Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): Head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model

Robert D. Bruno,Tadas S. Vasaitis,et al.

201176 citations

Mechanistic Relationship between Androgen Receptor Polyglutamine Tract Truncation and Androgen-dependent Transcriptional Hyperactivity in Prostate Cancer Cells

Qianben Wang,T.S. Udayakumar,et al.

200449 citations

Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors

Vânia M. Moreira,Tadas S. Vasaitis,et al.

200744 citations