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Luís A. R. Carvalho | Researchclopedia

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Luís A. R. Carvalho

University of Cambridge ORCID

18

Works

285

Citations

9

h-index

8

i10-index

Research Topics

Peptidase Inhibition and Analysis Chemical Synthesis and Analysis Click Chemistry and Applications

Affiliations

Scripps Research Institute2022–2022

University of Lisbon2013–2023

Instituto Politécnico de Lisboa2015–2015

University of Cambridge2022–2026

The Francis Crick Institute2026–2026

Top Works

Recovery of Depleted miR-146a in ALS Cortical Astrocytes Reverts Cell Aberrancies and Prevents Paracrine Pathogenicity on Microglia and Motor Neurons

Marta Barbosa,Cátia Gomes,et al.

202162 citations

Protease and Inhibitor Mechanisms

Neuropeptides and Animal Physiology

Phenotypic Effects of Wild-Type and Mutant SOD1 Expression in N9 Murine Microglia at Steady State, Inflammatory and Immunomodulatory Conditions

Ana Rita Vaz,Sara Pinto,et al.

201951 citations

Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation

Ana S. Falcão,Luís A. R. Carvalho,et al.

201639 citations

Clickable 4‐Oxo‐β‐lactam‐Based Selective Probing for Human Neutrophil Elastase Related Proteomes

E. F. P. Ruivo,Lídia Gonçalves,et al.

201638 citations

Optimization of <i>O</i><sub>3</sub>-Acyl Kojic Acid Derivatives as Potent and Selective Human Neutrophil Elastase Inhibitors

Susana D. Lucas,Lídia Gonçalves,et al.

201329 citations

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Luís A. R. Carvalho,B. Ross,et al.

202213 citations

3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling

Luís A. R. Carvalho,V.T. Almeida,et al.

202013 citations

The Impact of Activity‐Based Protein Profiling in Malaria Drug Discovery

Luís A. R. Carvalho,Gonçalo J. L. Bernardes

202212 citations

Selective Inhibition of Bruton’s Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors

Bárbara B. Sousa,Cátia Rebelo de Almeida,et al.

20229 citations