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Shimon Sakaguchi | Researchclopedia

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Shimon Sakaguchi

Kyoto University

8

Works

10,152

Citations

8

h-index

8

i10-index

Research Topics

T-cell and B-cell Immunology Immune Cell Function and Interaction Diabetes and associated disorders

Affiliations

Kyoto University1988–2001

University of California San Diego1992–1992

Tokyo Metropolitan Institute of Medical Science1996–1996

ARCH Development Corporation1995–1995

Institute of Immunology1988–1988

Top Works

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi,N Sakaguchi,et al.

19955,434 citations

Immunotherapy and Immune Responses

Immunodeficiency and Autoimmune Disorders

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

Takamune Takahashi,Yuhshi Kuniyasu,et al.

19981,546 citations

Immunologic tolerance maintained by CD25<sup>+</sup> CD4<sup>+</sup> regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

Shimon Sakaguchi,Noriko Sakaguchi,et al.

20011,512 citations

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.

M Asano,Masaaki Toda,et al.

19961,306 citations

T Cell-Mediated Maintenance of Natural Self-Tolerance: its Breakdown as a Possible Cause of Various Autoimmune Diseases

Shimon Sakaguchi,Masaaki Toda,et al.

1996172 citations

Immunologic and clinical studies on murine experimental autoimmune gastritis induced by neonatal thymectomy

K Fukuma,Shimon Sakaguchi,et al.

1988117 citations

Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: implications for autoimmunity and tumor immunity

Shimon Sakaguchi,Takeshi Takahashi,et al.

200155 citations

Causes and Mechanism of Autoimmune Disease: Cyclosporin A as a Probe for the Investigation

Noriko Sakaguchi,Shimon Sakaguchi

199211 citations