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David R. Mole | Researchclopedia

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David R. Mole

Australian National University ORCID

162

Works

17,842

Citations

47

h-index

60

i10-index

Research Topics

Cancer, Hypoxia, and Metabolism RNA modifications and cancer Epigenetics and DNA Methylation

Affiliations

Australian National University2024–2025

Geoscience Australia2022–2025

Centre for Human Genetics2000–2016

University of Padua2014–2014

The University of Western Australia2024–2025

Top Works

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola,David R. Mole,et al.

20015,474 citations

Renal and related cancers

Cancer Genomics and Diagnostics

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein,Jonathan Gleadle,et al.

20013,326 citations

Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

Matthew E. Cockman,Norma Masson,et al.

20001,046 citations

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Jennifer S. Isaacs,Yun Jin Jung,et al.

2005940 citations

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Johannes Schödel,Spyros Oikonomopoulos,et al.

2011723 citations

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

David R. Mole,Christine Blancher,et al.

2009545 citations

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

Sonny Ang,Hua Chen,et al.

2002499 citations

Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

Johannes Schödel,Steffen Grampp,et al.

2015409 citations

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

Hani Choudhry,Ashwag Albukhari,et al.

2014311 citations