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Michael Sinz | Researchclopedia

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Michael Sinz

122

Works

4,877

Citations

35

h-index

75

i10-index

Research Topics

Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms HIV/AIDS drug development and treatment

Affiliations

Rutgers, The State University of New Jersey2008–2008

University of North Carolina at Chapel Hill1999–1999

University of Maryland, Baltimore2008–2016

Merck & Co., Inc., Rahway, NJ, USA (United States)2016–2016

Roche (United States)2016–2016

Top Works

CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes

Gang Luo,Mark R. Cunningham,et al.

2002446 citations

Pharmacological Effects and Toxicity Studies

Hormonal Regulation and Hypertension

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

Kan He,K. R. Krishna Iyer,et al.

1998312 citations

Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole

Haiyan Huang,H Wang,et al.

2006208 citations

Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032)

Fiona McPhee,Amy K. Sheaffer,et al.

2012183 citations

Pharmacokinetic Drug Interactions Involving 17??-Ethinylestradiol

Hongjian Zhang,Donghui Cui,et al.

2007171 citations

Evaluation of 170 Xenobiotics as Transactivators of Human Pregnane X Receptor (hPXR) and Correlation to Known CYP3A4 Drug Interactions

Michael Sinz,Sean Kim,et al.

2006164 citations

In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

Valeria Chu,Heidi J. Einolf,et al.

2009161 citations

Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites

Sean Ekins,Cheng Chang,et al.

2007146 citations

Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical

Michael Sinz,Gillian Wallace,et al.

2008141 citations