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John C. Castle | Researchclopedia

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John C. Castle

University Hospitals Sussex NHS Foundation Trust ORCID

81

Works

13,885

Citations

40

h-index

59

i10-index

Research Topics

vaccines and immunoinformatics approaches RNA Research and Splicing Immunotherapy and Immune Responses

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)2003–2009

Mount Sinai Beth Israel1988–1988

Howard Hughes Medical Institute2005–2005

Baylor College of Medicine2005–2005

Johannes Gutenberg University Mainz2012–2018

Top Works

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim,Nelson C. Lau,et al.

20054,764 citations

RNA modifications and cancer

RNA and protein synthesis mechanisms

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

Jason M. Johnson,John C. Castle,et al.

20031,417 citations

An integrative genomics approach to infer causal associations between gene expression and disease

Eric E. Schadt,John R. Lamb,et al.

20051,062 citations

Exploiting the Mutanome for Tumor Vaccination

John C. Castle,Sebastian Kreiter,et al.

2012815 citations

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

Auinash Kalsotra,Xinshu Xiao,et al.

2008507 citations

Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2

Juan I. Young,Eugene P. Hong,et al.

2005479 citations

Experimental annotation of the human genome using microarray technology

Daniel Shoemaker,Eric E. Schadt,et al.

2001442 citations

Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines

John C. Castle,Chaolin Zhang,et al.

2008322 citations

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

Chaolin Zhang,Zuo‐Feng Zhang,et al.

2008303 citations