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Alexander J. Smith | Researchclopedia

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Alexander J. Smith

Guy's Hospital ORCID

225

Works

16,014

Citations

66

h-index

135

i10-index

Research Topics

Retinal Development and Disorders Retinal Diseases and Treatments Virus-based gene therapy research

Affiliations

Boston University2019–2019

University of London2003–2004

University College Hospital2012–2012

Guy's Hospital2021–2025

Georgia Institute of Technology1973–1973

Top Works

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

James Bainbridge,Alexander J. Smith,et al.

20081,914 citations

Photoreceptor and optogenetics research

Drug Transport and Resistance Mechanisms

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

Ardy van Helvoort,Alexander J. Smith,et al.

1996866 citations

Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis

James Bainbridge,Manjit Mehat,et al.

2015722 citations

MRP3, an organic anion transporter able to transport anti-cancer drugs

Marcel Kool,Marcel van der Linden,et al.

1999648 citations

Restoration of vision after transplantation of photoreceptors

R. A. Pearson,Amanda C. Barber,et al.

2012491 citations

Effective gene therapy with nonintegrating lentiviral vectors

Rafael J. Yáñez‐Muñoz,Kamaljit S. Balaggan,et al.

2006456 citations

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

Anai Gonzalez-Cordero,Emma L. West,et al.

2013370 citations

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

Alexander J. Smith,Xiaoming Yao,et al.

2017360 citations

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors

R. A. Pearson,Anai Gonzalez-Cordero,et al.

2016315 citations